Abstract Background Shoulder pain is one of the most common presentations of musculoskeletal pain with a 1-month population prevalence of between 7 and 26%.The overall prognosis of shoulder pain is highly variable with 40% of patients reporting persistent pain 1 year after consulting their primary care 5mm clinician.Despite evidence for prognostic

Background: Paravertebral muscles (PVM) degeneration (PMD) is closely associated with low back pain.Muscle stem cells (MuSCs) can promote muscle regeneration and repair.However, our understanding of the cellular composition of PVM and the key genes-mediated MuSCs functions is limited.Methods: We analyzed cells heterogeneity and identified key genes

Excessive risk-taking of financial agents drew a lot of attention in the aftermath of the financial crisis.Low interest rates and subdued market volatility during the Great Moderation are sometimes blamed for stimulating risk-taking and leading to the recent financial crisis.In recent years, with many central banks around the world conducting the p

Nephrotoxicity is substantial side effect for 30% of patients undergoing cancer therapy with cisplatin and may force them to change or even abandon the treatment.Studies regarding aerobic exercise have shown its efficacy for the Cross Bar treatment of many types of diseases and its capacity to reduce tumors.However, little is known about the impact

Photosynthesis in chloroplasts during the day and mitochondrial respiration during the night execute nearly opposing reactions that are coordinated with the internal cellular status and the external conditions.Here, we describe a mechanism by which the Arabidopsis clock component TIMING OF CAB EXPRESSION1 (TOC1) contributes to the diurnal regulatio